Randomized controlled trials (RCT) of psychotherapeutic interventions have addressed depression and demoralization associated with acute coronary syndromes. The present trial introduces psychological well-being, an increasingly recognized factor in cardiovascular health, as a therapeutic target. This study was designed to determine whether the sequential combination of cognitive-behavioral therapy (CBT) and well-being therapy (WBT) may yield more favorable outcomes than an active control group (clinical management) and to identify subgroups of patients at greater risk for cardiac negative outcomes.
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